Livestock sector has an important role in the socio-economic status of the large rural population of India. Topography and climatic condition of Kerala are most favorable for the survival of parasitic fauna. Helminthic infections that account for a major part of the diseases in domestic animals have been found to be a vital blow to bovine  production. Among the diseases due to gastro intestinal helminth parasites, amphistomosis is now  regarded as of great economic importance. An investigation was carried out to find out the economic impact of amphistomosis on production in cattle, of Quilandy municipality area of Kozhikode district.