Research Articles (Published online: 15-12-2021)
Malignant Histiocytoma of Spleen in a Lioness (Panthera leo)
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Malignant fibrous histiocytoma (MFH) or
malignant tumor originating from histiocytes has
been reported only rarely in animals (Marcin et al.,
2009). In most reported animal cases, it has been
described as single, often invasive, soft tissue mass in
skin or subcutis. Most spleenic masses described in
c a n i n e s a r e e i t h e r h e m a n g i o m a s o r
hemangiosarcomas while in felines they are mast cell
tumors or lymphosarcomas (Moulton, 1990).
Hendrick et al., 1992 described six cases of
malignant fibrous histiocytoma in canine spleen.

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Article history: Received: 15-12-2021, Accepted : 15-12-2021, Published online: 15-12-2021